Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16371043 | 0.99 | FKBP1A (0.49) | SMN1; SMN2FKBP1APOLBGAAHPGD | |
| SCHEMBL16370882 | 0.84 | CYP1A2 (0.47) | FKBP1AHPGDTP53MEN1KMT2A | |
| SCHEMBL16370936 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2FKBP1AHPGDNPC1RAB9A | |
| SCHEMBL16371130 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2FKBP1APOLBGAATP53 | |
| SCHEMBL16371037 | 0.82 | KMT2A (0.51) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL16370623 | 0.81 | MEN1 (0.56) | SMN1; SMN2FKBP1APOLBGAAHPGD | |
| SCHEMBL16370596 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHPGDNPC1RAB9A | |
| SCHEMBL16370542 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDTP53MEN1KMT2A | |
| SCHEMBL6832889 | 0.72 | CHRNB2 (0.39) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21775573 | 0.71 | TDP1 (0.46) | SMN1; SMN2FKBP1APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | claimed |
| WO-2015004485-A1 | THERAPEUTIC COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2015-01-15 | — | — | WO | disclosed |