SCHEMBL1637246

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL258689	0.95	PIM1 (0.55)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL10227215	0.93	PIM1 (0.50)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL30693959	0.91	PIM1 (0.48)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL3771900	0.91	PIM1 (0.48)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL19561508	0.90	PIM1 (0.52)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL25620895	0.89	MAPT (0.55)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL21824208	0.88	GABRP (0.46)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL10227267	0.85	PIM1 (0.52)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL29886872	0.84	MAPT (0.59)	PIM1GABRPGABRDGABRA1GABRB1
	SCHEMBL635182	0.84	MAPT (0.59)	PIM1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.