Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10732632 | 0.98 | KDM4E (0.55) | KDM4EKMT2AMAPTATMPKM | |
| Acetic Acid SCHEMBL28971363 | 0.95 | KDM4E (0.53) | KDM4EKMT2AMAPTATMPKM | |
| Sulfuric Acid SCHEMBL28971359 | 0.93 | KDM4E (0.59) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL31150256 | 0.84 | KDM4E (0.44) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL3369562 | 0.82 | KDM4E (0.58) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL189938 | 0.81 | ALDH1A1 (0.49) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL27780614 | 0.81 | KDM4E (0.40) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL23460209 | 0.81 | KDM4E (0.57) | KDM4EKMT2AMAPTATMPKM | |
| SCHEMBL3230676 | 0.81 | KDM4E (0.57) | KDM4EKMT2AMAPTATMPOLB | |
| SCHEMBL1845347 | 0.81 | KDM4E (0.57) | KDM4EKMT2AMAPTATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806543-A | Articaine hydrochloride intermediate and preparation method and application thereof | 济南宣正药业有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-217120215-U | Heating device for synthesizing 3-amino-4-methylthiophene-2-methyl formate | 济南宣正药业有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-106699724-B | A method of recycling articaine hydrochloride or in which product from synthesis mother liquid | 蚌埠丰原涂山制药有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-108299382-A | A kind of preparation method of articaine hydrochloride intermediate | 常州沃腾化工科技有限公司 | 2018-07-20 | — | — | CN | claimed |
| CN-106699724-A | Method for recovering articaine hydrochloride or intermediate products thereof in self-synthetic mother liquor | 蚌埠丰原涂山制药有限公司 | 2017-05-24 | — | — | CN | claimed |
| EP-2556062-B1 | AMIDE DERIVATIVES OF AVENALUMIC ACID, PROCESS FOR PREPARING SAME AND COSMETIC COMPOSITIONS CONTAINING SAME | PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) | 2017-01-04 | — | — | EP | claimed |
| EP-2170872-B1 | PROCESS FOR THE PREPARATION OF THE N-(2-CHLORO-4-METHYL-3-THIENYL)-1H- BENZIMIDAZOL-2-AMINE HYDROCHLORIDE AND INTERMEDIATES THEREOF | SANOFI AVENTIS US LLC (US) | 2010-09-01 | — | — | EP | claimed |
| US-20100174088-A1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL AS SODIUM/PROTON EXCHANGER TYPE 3 INHIBITORS | SANOFI-AVENTIS U.S. LLC (US) | 2010-07-08 | — | — | US | claimed |
| EP-2170872-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND INTERMEDIATES THEREOF | Sanofi-Aventis U.S. LLC (US) | 2010-04-07 | — | — | EP | claimed |
| WO-2009006066-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND INTERMEDIATES THEREOF | SANOFI-AVENTIS U.S. LLC (US) | 2009-01-08 | — | — | WO | claimed |
| EP-4747261-A1 | AMINOPYRIMIDINE DERIVATIVES AS CYCLIN-DEPENDENT KINASE INHIBITORS | Accutar Biotechnology Inc. (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2026104680-A1 | NOVEL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2026-05-21 | — | — | WO | disclosed |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | NodThera Limited (GB) | 2026-05-12 | — | — | US | disclosed |
| EP-3901151-B1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2026-04-01 | — | — | EP | disclosed |
| EP-4713095-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | Chengdu Anticancer Bioscience, Ltd. (CN) | 2026-03-25 | — | — | EP | disclosed |
| EP-0298542-A1 | Process for preparing thiophene derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-01-11 | — | — | EP | disclosed |
| US-4666502-A | Herbicidal N-thienyl-chloroacetamides | SANDOZ LTD. (CH) | 1987-05-19 | — | — | US | disclosed |
| US-4472425-A | FUNGICIDES | SANDOZ LTD. (CH) | 1984-09-18 | — | — | US | disclosed |
| US-4442289-A | ANTIASTHMA | HOFFMANN-LA ROCHE INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4376121-A | Antiallerigically-active imidazothienopyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1983-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174088-A1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL AS SODIUM/PROTON EXCHANGER TYPE 3 INHIBITORS | SLC9A3, NHERF1, SLC9A5 | KDM4E 1734/4885KMT2A 1001/4885MAPT 4075/4885 |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | PYCARD, NOD1, NLRP3 | KDM4E 3454/4885KMT2A 4104/4885MAPT 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.