Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930851 | 0.81 | ADORA3 (0.41) | ADORA3KDM4EMAPTKMT2APIK3CA | |
| SCHEMBL163726 | 0.79 | PTGS1 (0.48) | ADORA3KDM4EMAPTKMT2APIK3CA | |
| SCHEMBL164349 | 0.75 | NOTUM (0.42) | ANO1KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL163673 | 0.75 | NPC1 (0.44) | ADORA3MAPTADORA2AMAPK1PIK3CG | |
| SCHEMBL164662 | 0.71 | GRM5 (0.55) | KDM4EMAPTKMT2AADORA2AADORA1 | |
| SCHEMBL16039103 | 0.71 | ANO1 (0.45) | ANO1ADORA3KDM4EMAPTKMT2A | |
| SCHEMBL3264375 | 0.69 | CASP3 (0.55) | ANO1KDM4EMAPTKMT2APIK3CA | |
| SCHEMBL164860 | 0.65 | POLB (0.47) | KDM4EMAPTKMT2ALMNACYP1A2 | |
| SCHEMBL3263006 | 0.65 | ALOX15 (0.43) | ANO1ADORA3KDM4EMAPTKMT2A | |
| SCHEMBL25842528 | 0.64 | CYP19A1 (0.39) | KDM4EKMT2ALMNACYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | claimed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | claimed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | claimed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | claimed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | claimed |
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | disclosed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | disclosed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | disclosed |
| EP-2611786-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | Monsanto Technology LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030887-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | DIVERGENCE, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012030887-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | DIVERGENCE, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | ANO1 2245/4885ADORA3 3536/4885KDM4E 789/4885 |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | ANO1 2454/4885ADORA3 3504/4885KDM4E 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.