SCHEMBL1637306

SCHEMBL1637306

O=[N+]([O-])c1ccc([N+](=O)[O-])c(F)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
HIF1A Q16665 1/20 0.70
TDP1 Q9NUW8 4/20 0.67
ATM Q13315 1/20 0.67
GPR35 Q9HC97 2/20 0.59
TSHR P16473 3/20 0.53
TP53 P04637 1/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TXNRD1 Q16881 1/20 0.52
TXNRD3 Q86VQ6 1/20 0.52
TXNRD2 Q9NNW7 1/20 0.52
HSPB1 P04792 3/20 0.51
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.47
HSD17B10 Q99714 1/20 0.47
VCAM1 P19320 1/20 0.46
PTPRC P08575 1/20 0.45
S100A4 P26447 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31474855 1.00 ALDH1A1 (0.70) ALDH1A1HIF1ATDP1ATMGPR35
Formic Acid SCHEMBL28202419 0.91 ALDH1A1 (0.59) ALDH1A1HIF1ATDP1ATMGPR35
SCHEMBL27739457 0.88 TDP1 (0.73) ALDH1A1HIF1ATDP1ATMGPR35
SCHEMBL35276 0.83 ALDH1A1 (1.00) ALDH1A1HIF1ATDP1ATMGPR35
SCHEMBL27715742 0.83 ALDH1A1 (1.00) ALDH1A1HIF1ATDP1ATMGPR35
SCHEMBL29349904 0.83 ALDH1A1 (1.00) ALDH1A1HIF1ATDP1ATMGPR35
SCHEMBL29379039 0.82 ALDH1A1 (0.69) ALDH1A1HIF1ATDP1GPR35TSHR
SCHEMBL85604 0.82 ALDH1A1 (0.69) ALDH1A1HIF1ATDP1GPR35TSHR
SCHEMBL28252591 0.82 ALDH1A1 (0.69) ALDH1A1HIF1ATDP1GPR35TSHR
SCHEMBL28309178 0.81 ALDH1A1 (0.96) ALDH1A1HIF1ATDP1ATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110527092-A A method of preparing high molecular weight poly arylidene thio-ester sulfone ZHUHAI CHANGXIAN NEW MATERIALS TECH CO LTD 2019-12-03 CN claimed
CN-105621587-B A kind of method using potentiometric titrations degradating chloro nitro-aromatic 浙江大学 2018-01-23 CN claimed
US-20250250240-A1 PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX UNIVERSITE D'AIX-MARSEILLE (FR) 2025-08-07 US disclosed
EP-4466254-A1 PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX Université d'Aix Marseille (FR) 2024-11-27 EP disclosed
WO-2023139263-A1 PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX UNIVERSITE D'AIX-MARSEILLE (FR) 2023-07-27 WO disclosed
CN-112812711-B High-reactivity metal-rubber hot vulcanization adhesive and application method thereof 安徽普力通新材料科技有限公司 2023-07-18 CN disclosed
CN-112023046-B Application of miR-2115in diagnosis and treatment of atopic dermatitis 河北仁博科技有限公司 2022-05-10 CN disclosed
CN-112094895-B MiRNA for diagnosis and treatment of atopic dermatitis 河北仁博科技有限公司 2021-08-13 CN disclosed
CN-112812711-A High-reactivity metal-rubber heat-vulcanization adhesive and using method thereof 安徽普力通新材料科技有限公司 2021-05-18 CN disclosed
CN-112094895-A MiRNA for diagnosis and treatment of atopic dermatitis 河北仁博科技有限公司 2020-12-18 CN disclosed
CN-112023046-A Application of miR-2115in diagnosis and treatment of atopic dermatitis 河北仁博科技有限公司 2020-12-04 CN disclosed
US-6329344-B1 UREA DERIVATIVE OF ALKYLENE DIOXYFURAN ETHERS RANBAXY LABORATORIES LIMITED (IN) 2001-12-11 US disclosed
EP-1144425-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES, LTD. (IN) 2001-10-17 EP disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
WO-2000042053-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (US) 2000-07-20 WO disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0270964-B1 PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES BAYER AG (DE) 1992-07-08 EP disclosed
US-4868347-A SOLVENT EXTRACTION BAYER AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
EP-0270964-A2 Process for obtaining substituted fluorobenzenes BAYER AG (DE) 1988-06-15 EP disclosed
EP-0237899-A1 Production of fluoroaniline derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250240-A1 PHENAZINE COMPOUND FOR MEASURING BACTERIAL EFFLUX ABCC5, ABCB11, TMEM165 ALDH1A1 2835/4885HIF1A 2516/4885TDP1 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.