SCHEMBL1635653

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1635433	0.96	PLA2G2A (0.40)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL19986439	0.96	PLA2G2A (0.42)	PLA2G2APLA2G4APRKDCPGRGAA
	SCHEMBL1637407	0.94	PLA2G2A (0.41)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL1637658	0.93	PRKDC (0.40)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL1636090	0.93	PLA2G2A (0.40)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL9889918	0.91	PDK2 (0.34)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL20277263	0.90	PLA2G2A (0.46)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL12181453	0.90	PRKDC (0.38)	PLA2G2APLA2G4APDK2PRKDCPGR
	SCHEMBL17944321	0.89	PGR (0.40)	PLA2G2APLA2G4APDK2PGRPLA2G10
	SCHEMBL16788582	0.88	PLA2G2A (0.44)	PLA2G2APLA2G4APDK2PRKDCPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.