Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16313177 | 1.00 | MAPT (0.50) | MAPTALDH1A1KMT2ANR4A1RAB9A | |
| SCHEMBL7134286 | 0.99 | MAPT (0.51) | MAPTALDH1A1KMT2ANR4A1RAB9A | |
| SCHEMBL7477981 | 0.88 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL163753 | 0.88 | AKR1C3 (0.52) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1962366 | 0.88 | KMT2A (0.48) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27165409 | 0.88 | AKR1C3 (0.52) | MAPTALDH1A1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8512751 | 0.87 | HDAC6 (0.43) | MAPTALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL25954126 | 0.83 | TERT (0.41) | MAPTALDH1A1KMT2ARAB9AMCL1 | |
| SCHEMBL21940997 | 0.82 | RAB9A (0.46) | MAPTALDH1A1KMT2ARAB9AHPGD | |
| SCHEMBL3143230 | 0.82 | RAB9A (0.46) | MAPTALDH1A1KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136213-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-20 | — | — | WO | disclosed |
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | disclosed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
| US-6478988-B1 | Photochromic substituted naphthopyran compounds | BMC VISION-EASE LENS, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-0973761-B1 | RED COLOURING HYPERCHROMIC 3H-NAPHTHO 2,1-b ]PYRANS | JAMES ROBINSON LTD (GB) | 2002-07-03 | — | — | EP | disclosed |
| US-6294112-B1 | Red coloring hyperchromic 3H-naphtho[2,1-B]pyrans | JAMES ROBINSON LIMITED (GB) | 2001-09-25 | — | — | US | disclosed |
| EP-1016702-A2 | Photochromic substituted naphthopyran compounds | BMC Vision-Ease Lens Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | MAPT 573/4885ALDH1A1 1243/4885KMT2A 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.