Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26916041 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TP53MAPTLMNAPOLB | |
| SCHEMBL6602598 | 0.77 | GAA (0.38) | ALDH1A1LMNAPOLBGAARXRA | |
| SCHEMBL14912168 | 0.72 | ALDH1A1 (0.50) | ALDH1A1TP53MAPTLMNAHSD11B1 | |
| SCHEMBL23684595 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAPOLBHSD11B1 | |
| SCHEMBL14279899 | 0.69 | GAA (0.30) | GAA | |
| SCHEMBL22533326 | 0.69 | CYP4F2 (0.44) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL21986866 | 0.68 | CYP4F2 (0.37) | ALDH1A1GAARXRARXRBRXRG | |
| SCHEMBL2816857 | 0.68 | LMNA (0.42) | ALDH1A1LMNAHSD11B1L3MBTL1TSHR | |
| SCHEMBL6768903 | 0.68 | ALDH1A1 (0.38) | ALDH1A1TP53MAPTLMNAPOLB | |
| SCHEMBL25183987 | 0.66 | CYP4F2 (0.37) | ALDH1A1LMNAPOLBGAARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724263-B1 | BASIC AMINE COMPOUND AND USE THEREOF | KUREHA CORP (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | KUREHA CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7932281-B2 | Amine-based compound and use thereof | KUREHA CORPORATION (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20080071091-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | WYETH (US) | 2008-03-20 | — | — | US | disclosed |
| US-20080071091-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | WYETH (US) | 2008-03-20 | — | — | US | disclosed |
| US-7323483-B2 | Processes and compounds for the preparation of substituted naphthylindole derivatives | WYETH (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323483-B2 | Processes and compounds for the preparation of substituted naphthylindole derivatives | WYETH (US) | 2008-01-29 | — | — | US | disclosed |
| US-20070208007-A1 | Amine-Based Compound and Use Thereof | KUREHA CORPORATION (JP) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | NR0B2, NR5A2, NR1D2 | ALDH1A1 2045/4885TP53 2720/4885MAPT 3333/4885 |
| US-20080071091-A1 | PROCESSES AND COMPOUNDS FOR THE PREPARATION OF SUBSTITUTED NAPHTHYLINDOLE DERIVATIVES | SERPINE1, SERPINB1, TFPI | ALDH1A1 214/4885TP53 1379/4885MAPT 3710/4885 |
| US-20070208007-A1 | Amine-Based Compound and Use Thereof | NR0B2, NR5A2, NR2E1 | ALDH1A1 1901/4885TP53 3064/4885MAPT 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.