Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20960631 | 0.81 | ALDH1A1 (0.58) | ALDH1A1RECQLGAALMNA | |
| SCHEMBL16377107 | 0.72 | HSD11B1 (0.51) | HSD11B1GPR84 | |
| SCHEMBL15755125 | 0.72 | HSD11B1 (0.51) | HSD11B1GPR84 | |
| SCHEMBL11137789 | 0.71 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKCNH2NPC1 | |
| SCHEMBL11134767 | 0.71 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKCNH2NPC1 | |
| SCHEMBL19027659 | 0.70 | HSD11B1 (0.52) | HSD11B1GPR84 | |
| SCHEMBL7561044 | 0.69 | TOP2A (0.47) | MEN1KMT2ANPC1 | |
| SCHEMBL29843944 | 0.67 | PTGS2 (0.50) | HSD11B1ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL27909193 | 0.67 | PTGS2 (0.50) | HSD11B1ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL9797528 | 0.67 | RARB (0.62) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150001509-A1 | COMPOSITION | CAMBRIDGE DISPLAY TECHNOLOGY, LTD (GB) | 2015-01-01 | — | — | US | disclosed |