SCHEMBL1637805

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636396	0.97	ALOX5 (0.44)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1636394	0.94	ALOX5 (0.42)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL10226270	0.94	PRKDC (0.40)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1637271	0.92	PRKDC (0.40)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1635736	0.92	PRKDC (0.46)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1635745	0.92	PRKDC (0.46)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1636326	0.89	ALOX5 (0.44)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL9889990	0.88	TSHR (0.40)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA
	SCHEMBL1636331	0.87	ALDH1A1 (0.42)	PRKDCALOX5ALDH1A1PIK3CDPIK3CB
	SCHEMBL11713826	0.87	PRKDC (0.47)	PRKDCALOX5ALDH1A1PIK3CDPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.