SCHEMBL1636331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636389	0.88	ALOX5 (0.40)	ALDH1A1KDM4EMAPTHSD17B10HPGD
	SCHEMBL1637805	0.87	PRKDC (0.43)	ALDH1A1KDM4EHSD17B10HPGDTP53
	SCHEMBL22947312	0.86	ALDH1A1 (0.43)	ALDH1A1KDM4EMAPTHSD17B10HPGD
	SCHEMBL1636396	0.84	ALOX5 (0.44)	ALDH1A1KDM4EHSD17B10TP53TSHR
	SCHEMBL1636391	0.84	PRKDC (0.46)	ALDH1A1KDM4EMAPTHSD17B10TP53
	SCHEMBL1635745	0.83	PRKDC (0.46)	ALDH1A1KDM4EHSD17B10TP53TSHR
	SCHEMBL1637271	0.83	PRKDC (0.40)	ALDH1A1KDM4EHSD17B10TP53TSHR
	SCHEMBL1635736	0.83	PRKDC (0.46)	ALDH1A1KDM4EHSD17B10TP53TSHR
	SCHEMBL10226270	0.81	PRKDC (0.40)	ALDH1A1KDM4EHSD17B10TP53TSHR
	SCHEMBL1636394	0.81	ALOX5 (0.42)	ALDH1A1KDM4EHSD17B10TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.