Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296493 | 0.86 | DGAT1 (0.42) | DGAT1ELANE | |
| SCHEMBL13971692 | 0.85 | DGAT1 (0.43) | DGAT1L3MBTL1 | |
| SCHEMBL26796498 | 0.81 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL14307992 | 0.79 | PARP1 (0.54) | DGAT1L3MBTL1KDM4EPARP1 | |
| SCHEMBL13972035 | 0.78 | DGAT1 (0.37) | DGAT1ELANE | |
| SCHEMBL4303943 | 0.78 | KDM4E (0.49) | DGAT1KDM4E | |
| SCHEMBL3723418 | 0.77 | DGAT1 (0.35) | DGAT1KDM4EPARP1 | |
| SCHEMBL3724057 | 0.76 | POLB (0.35) | DGAT1L3MBTL1KDM4E | |
| SCHEMBL3748782 | 0.74 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL3754178 | 0.73 | HSD11B1 (0.47) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133204-B2 | 5-membered heterocyclic amides and related compounds | H. LUNDBECK A/S (DK) | 2015-09-15 | — | — | US | disclosed |
| US-20150005293-A1 | 5-Membered Heterocyclic Amides And Related Compounds | MINDIMMUNE THERAPEUTICS, INC. | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005293-A1 | 5-Membered Heterocyclic Amides And Related Compounds | GPR35, HCAR2, HCAR1 | DGAT1 3593/4885L3MBTL1 4052/4885KDM4E 3311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.