Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203384 | 0.82 | PIK3CA (0.44) | HDAC6PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2705988 | 0.81 | LOXL2 (0.54) | TRPV1HDAC6PIK3CDPIK3CAPIK3CB | |
| SCHEMBL13862771 | 0.79 | TRPV1 (0.58) | TRPV1TNFNOD1HDAC3HDAC1 | |
| SCHEMBL15125604 | 0.77 | TRPV1 (0.53) | TRPV1TNFNOD1HDAC3HDAC1 | |
| SCHEMBL203790 | 0.77 | ENPP3 (0.41) | LOXL2NPC1RAB9AGAAMAPK1 | |
| SCHEMBL7082892 | 0.76 | DYRK1A (0.49) | TRPV1 | |
| SCHEMBL12212172 | 0.75 | LIPG (0.55) | TRPV1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14791428 | 0.74 | NPC1 (0.59) | TRPV1TNFNOD1HDAC3HDAC1 | |
| SCHEMBL203263 | 0.73 | MAPT (0.47) | TRPV1HDAC6LOXL2NPC1RAB9A | |
| SCHEMBL201370 | 0.72 | DYRK1A (0.46) | TRPV1HDAC6LOXL2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011559-A1 | ANTIMICROBIAL AGENTS | TAXIS PHARMACEUTICALS, INC. | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011559-A1 | ANTIMICROBIAL AGENTS | CFTR, MPO, ATF1 | TRPV1 1881/4885TNF 461/4885NOD1 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.