SCHEMBL16385131

SCHEMBL16385131

Cc1cc(-c2ccc(F)cn2)c(C)cc1OCc1c(C2CC2)cccc1-n1nnn(C)c1=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
HTR6 P50406 1/20 0.32
MAPK1 P28482 1/20 0.31
MAPK14 Q16539 1/20 0.31
MAPKAPK5 Q8IW41 1/20 0.31
NOTUM Q6P988 1/20 0.31
DRD1 P21728 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16384951 0.89 MAPK14 (0.31) MAPK14
SCHEMBL17751230 0.89 NR1H4 (0.33) CNR2HTR6MAPK1MAPK14MAPKAPK5
SCHEMBL17886106 0.88 BRD4 (0.32) NOTUM
SCHEMBL16385565 0.88 PDK2 (0.35) DRD1
SCHEMBL17789254 0.88 GRM7 (0.35)
SCHEMBL17804267 0.87 DRD1 (0.31) CNR2NOTUMDRD1
SCHEMBL17788156 0.87 MAPK14 (0.35) MAPK14
SCHEMBL16384952 0.87 ATP4A (0.32) MAPK14
SCHEMBL16999058 0.85 HTR1A (0.31) HTR6NOTUMDRD1
SCHEMBL18427512 0.84 POLB (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 US disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 US disclosed
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 US disclosed
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 US disclosed
WO-2015005499-A1 TETRAZOLINONE COMPOUND AND USE THEREOF 住友化学株式会社 (JP) 2015-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SOD1, UQCRB, MT-CO1 CNR2 3151/4885HTR6 2049/4885MAPK1 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.