SCHEMBL176260

SCHEMBL176260

C=CCc1[c]cccc1CC=C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.34
AKR1B1 P15121 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32
AURKA O14965 1/20 0.31
DAPK3 O43293 1/20 0.31
MAP4K4 O95819 1/20 0.31
RET P07949 1/20 0.31
IGF1R P08069 1/20 0.31
MET P08581 1/20 0.31
PIM1 P11309 1/20 0.31
LTK P29376 1/20 0.31
KDR P35968 1/20 0.31
MAPK8 P45983 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9854766 0.86 GABRA1 (0.39) GABRA1GABRB2ALDH1A1KDM4EAKR1B1
SCHEMBL7395144 0.86 GABRA1 (0.39) GABRA1GABRB2ALDH1A1KDM4EAKR1B1
SCHEMBL6805441 0.83 GABRA1 (0.44) GABRA1GABRB2ALDH1A1KDM4EAKR1B1
SCHEMBL7687255 0.82 HTR2A (0.37) GABRA1GABRB2KDM4EMEN1KMT2A
SCHEMBL722829 0.81 CYP3A4 (0.35) GABRA1GABRB2
SCHEMBL11811972 0.79 THRA (0.40) KDM4EMAPT
SCHEMBL3267471 0.79 THRB (0.37) GABRA1GABRB2ALDH1A1KDM4EMEN1
SCHEMBL4020624 0.78 THRA (0.42) KDM4EMEN1KMT2AMAPT
SCHEMBL7726842 0.78 THRA (0.39) GABRA1GABRB2MEN1KMT2A
SCHEMBL5604556 0.78 CYP3A4 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115895257-B Method for improving surface quality of bismaleimide resin condensate 中国航发北京航空材料研究院 2024-06-21 CN claimed
CN-115232310-B High-temperature-resistant toughness bismaleimide resin and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-04-09 CN claimed
WO-2024046539-A1 EMITTER MATERIAL FOR OLEDS TECHNISCHE UNIVERSITÄT DORTMUND (DE) 2024-03-07 WO claimed
CN-114213631-B Resin toughening composition, resin toughening modifier, modified bismaleimide resin composition and cured product 洛阳尖端技术研究院 2024-02-06 CN claimed
US-RE49735-E1 Oxazolidinones as modulators of MGLUR5 BRISTOL-MYERS SQUIBB COMPANY (US) 2023-11-28 US claimed
CN-116947899-A Carborane gas-induced color-changing luminescent material, and preparation method and application thereof 盐城工学院 2023-10-27 CN claimed
US-20230317967-A1 ORGANO-ALUMINUM ANALYTES FOR NONAQUEOUS REDOX FLOW BATTERIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 US claimed
WO-2023115686-A1 HALOGEN-FREE AND PHOSPHORUS-FREE FLAME-RETARDANT SHAPE MEMORY BISMALEIMIDE RESIN AND PREPARATION METHOD THEREFOR 苏州大学 2023-06-29 WO claimed
CN-114195769-B Polyimide modifier, composition and preparation method thereof 航天科工(长沙)新材料研究院有限公司 2023-05-30 CN claimed
CN-115895257-A Method for improving surface quality of bismaleimide resin cured product 中国航发北京航空材料研究院 2023-04-04 CN claimed
US-4457373-A CARBOXYMETHYLATED ETHOXYLATE CHEMISCHE WERKE HUELS, A.G. (DE) 1984-07-03 US claimed
US-4418217-A TENSIDES FOR WETTING, WASHING OR CLEANSING AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1983-11-29 US claimed
EP-0085404-A1 Stabilized linear low density polyethylene BORG-WARNER CHEMICALS INC. (US) 1983-08-10 EP claimed
US-4384965-A Method for the mechanical working of metals and lubricant concentrate BEROL KEMI AB (SE) 1983-05-24 US claimed
EP-0002773-B1 PROCESS FOR CONDITIONING AND HYDROPHOBING OF LEATHER CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP claimed
US-4289665-A FAT LIQUORS AND NONIONIC OR ANIONIC SURFACTANTS CASSELLA AKTIENGESELLSCHAFT (DE) 1981-09-15 US claimed
EP-0034132-A2 Method for the mechanical working of metals and lubricant concentrate BEROL KEMI AB (SE) 1981-08-19 EP claimed
US-4217228-A MIXTURE OF HYDROXY- AND HYDROCARBYL-SUBSTITUTED SILICONE OILS TH. GOLDSCHMIDT AG (DE) 1980-08-12 US claimed
EP-0002773-A2 Process for conditioning and hydrophobing of leather CASSELLA Aktiengesellschaft (DE) 1979-07-11 EP claimed
US-4055689-A ORGANIC PHOSPHATE CIBA-GEIGY CORPORATION (US) 1977-10-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230317967-A1 ORGANO-ALUMINUM ANALYTES FOR NONAQUEOUS REDOX FLOW BATTERIES NFE2L2, NQO1, SLC8B1 GABRA1 4495/4885GABRB2 3566/4885ALDH1A1 1144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.