SCHEMBL5454296

SCHEMBL5454296

C=CCc1ccc[c]c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.41
GABRB2 P47870 2/20 0.41
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
GAA P10253 1/20 0.36
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
AKR1B1 P15121 1/20 0.33
PPARG P37231 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
ADRB2 P07550 3/20 0.31
ADRB1 P08588 3/20 0.31
HTR1A P08908 1/20 0.31
ADRB3 P13945 1/20 0.31
ADRA2C P18825 1/20 0.31
SLC6A2 P23975 1/20 0.31
BDKRB2 P30411 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176260 0.78 GABRA1 (0.42) GABRA1GABRB2MEN1KMT2AGAA
SCHEMBL7928568 0.76 GABRA1 (0.33) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL1638775 0.76 GABRA1 (0.50) GABRA1GABRB2MEN1KMT2AGAA
SCHEMBL5091335 0.76 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL1515067 0.76 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL3661576 0.76 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AALDH1A1
SCHEMBL7761703 0.76 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AGAA
SCHEMBL4789832 0.76 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2AGAA
SCHEMBL11838516 0.76 ALDH1A1 (0.39) GABRA1GABRB2ALDH1A1LMNAPPARG
SCHEMBL8059533 0.74 MEN1 (0.35) GABRA1GABRB2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7189663-B2 Organic semiconductor device having an active dielectric layer comprising silsesquioxanes LUCENT TECHNOLOGIES INC. (US) 2007-03-13 US disclosed
EP-1285751-B1 Image recording material FUJI PHOTO FILM CO LTD (JP) 2006-08-09 EP disclosed
US-20050148129-A1 Organic semiconductor device having an active dielectric layer comprising silsesquioxanes LUCENT TECHNOLOGIES INC. 2005-07-07 US disclosed
US-6702437-B2 AQUEOUS ALKALINE SOLUBLE POLYMER HAVING CARBON-CARBON DOUBLE BOND SIDE CHAINS, LIGHT-HEAT CONVERTING AGENT AND FREE RADICAL INITIATOR; PLANOGRAPHIC PRINTING PLATE; PRINTING RESISTANCE; STORAGE STABILITY; STRENGTH OF IMAGE PORTION FUJI PHOTO FILM CO., LTD. (JP) 2004-03-09 US disclosed
US-20030146965-A1 AQUEOUS ALKALINE SOLUBLE POLYMER HAVING CARBON-CARBON DOUBLE BOND SIDE CHAINS, LIGHT-HEAT CONVERTING AGENT AND FREE RADICAL INITIATOR; PLANOGRAPHIC PRINTING PLATE; PRINTING RESISTANCE; STORAGE STABILITY; STRENGTH OF IMAGE PORTION FUJI PHOTO FILM CO., LTD. 2003-08-07 US disclosed
EP-1285751-A2 Image recording material FUJI PHOTO FILM CO., LTD. (JP) 2003-02-26 EP disclosed
US-5962113-A POLYSILOXANE-AMIDE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-10-05 US disclosed
US-5883219-A COMPRISING SUBSTRATE, METALLIC CIRCUIT LINES POSITIONED ON SUBSTRATE, AND POROUS DIELECTRIC MATERIAL POSITIONED ON THE CIRCUIT LINES; THE DIELECTRIC MATERIAL COMPRISES THE REACTION PRODUCT OF AN ORGANIC POLYSILICA AND POLYAMIC ESTER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1999-03-16 US disclosed
CN-1029227-C Composition for denatured denaturation or protection agent for nerve cell and process for preparing benzene derivatives used for composition OTSUKA PHARMA CO LTD (JP) 1995-07-05 CN disclosed
EP-0382213-B1 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMA CO LTD (JP) 1995-05-10 EP disclosed
US-5053548-A Containing hydroxy substituents; nervous system disorders OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) 1991-10-01 US disclosed
CN-1044807-A Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition OTSUKA PHARMA CO LTD (JP) 1990-08-22 CN disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed