Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15712058 | 0.88 | DPP4 (0.47) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15712104 | 0.79 | XIAP (0.33) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15334874 | 0.76 | DPP4 (0.33) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15334875 | 0.69 | DPP4 (0.35) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL16789728 | 0.66 | PSEN1 (0.32) | — | |
| SCHEMBL15712090 | 0.66 | DPP4 (0.41) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15028069 | 0.64 | DPP4 (0.48) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL15334872 | 0.63 | DPP4 (0.44) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL24633817 | 0.62 | ALDH1A1 (0.36) | DPP4 | |
| SCHEMBL12344003 | 0.62 | DPP4 (0.60) | DPP4DPP8DPP7DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933056-B2 | Soft protease inhibitors and pro-soft forms thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2015-01-13 | — | — | US | disclosed |