SCHEMBL16392602

SCHEMBL16392602

CN(CCCCCCN1C(=O)c2ccccc2C1=O)CC[C@H]1COC(C)(C)O1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.52
MAOB P27338 4/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18522656 0.86 CYP1A2 (0.52) ACHEMAOB
SCHEMBL20707236 0.86 CYP1A2 (0.52) ACHEMAOB
SCHEMBL752923 0.85 CYP1A2 (0.56) ACHE
SCHEMBL2399729 0.77 MAOB (0.77) ACHEMAOB
SCHEMBL2400817 0.76 MAOB (0.75) ACHEMAOB
SCHEMBL13590254 0.76 ACHE (0.73) ACHEMAOB
SCHEMBL7434719 0.75 ALDH1A1 (0.52) ACHE
SCHEMBL13590077 0.73 ACHE (0.68) ACHEMAOB
SCHEMBL14729859 0.73 MAOB (0.77) ACHEMAOB
SCHEMBL25443471 0.72 MAOB (0.74) ACHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation ALNYLAM PHARMACEUTICALS, INC. (US) 2020-10-20 US disclosed
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION BANK OF AMERICA, N.A. 2016-12-29 US disclosed
WO-2015006740-A2 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION ALNYLAM PHARMACEUTICALS, INC. (US) 2015-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160376585-A1 OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION IGF2R, IRS1, INSR ACHE 4533/4885MAOB 3130/4885
US-10808246-B2 Oligonucleotide-ligand conjugates and process for their preparation RTCB, IGF2BP2, SNRPE ACHE 4821/4885MAOB 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.