Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707236 | 1.00 | CYP1A2 (0.52) | CYP1A2CYP2C19CYP2C9ACHETDP1 | |
| SCHEMBL752923 | 0.96 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9ACHETDP1 | |
| SCHEMBL16392602 | 0.86 | ACHE (0.52) | ACHEMAOB | |
| SCHEMBL7434719 | 0.82 | ALDH1A1 (0.52) | CYP1A2CYP2C19CYP2C9ACHEKDM4E | |
| SCHEMBL12767468 | 0.81 | RECQL (0.46) | CYP1A2CYP2C19CYP2C9TDP1KDM4E | |
| SCHEMBL12767504 | 0.81 | RECQL (0.46) | CYP1A2CYP2C19CYP2C9TDP1KDM4E | |
| SCHEMBL8061487 | 0.81 | TDP1 (0.51) | CYP1A2CYP2C19CYP2C9TDP1KDM4E | |
| SCHEMBL8070914 | 0.79 | TDP1 (0.54) | CYP1A2CYP2C19CYP2C9TDP1ALDH1A1 | |
| SCHEMBL8071862 | 0.79 | TDP1 (0.54) | CYP1A2CYP2C19CYP2C9TDP1ALDH1A1 | |
| SCHEMBL12253437 | 0.78 | RAB9A (0.42) | CYP1A2CYP2C19CYP2C9ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529423-B2 | Biodegradable polyethylene glycol derivative having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| US-11041052-B2 | Biodegradable hydrogel having cyclic benzylidene acetal structure | NOF CORPORATION (JP) | 2021-06-22 | — | — | US | disclosed |
| EP-3130587-B1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3357514-B1 | LIPID DERIVATIVE IN WHICH HYDROPHILIC POLYMER IS BOUND VIA CYCLIC BENZYLIDENE ACETAL LINKERS | NOF CORP (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3279236-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| US-10808050-B2 | Antibody-drug conjugate having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2020-10-20 | — | — | US | disclosed |
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-20200289656-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-10626217-B2 | Lipid derivative in which hydrophilic polymer is bound through cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20190092906-A1 | BIODEGRADABLE HYDROGEL HAVING CYCLIC BENZYLIDENE ACETAL STRUCTURE | NOF CORPORATION (JP) | 2019-03-28 | — | — | US | disclosed |
| EP-3357514-A1 | LIPID DERIVATIVE IN WHICH HYDROPHILIC POLYMERS ARE BOUND VIA CYCLIC BENZYLIDENE ACETAL LINKERS | NOF Corporation (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-20180078651-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180078651-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20170290919-A1 | ANTIBODY-DRUG CONJUGATE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170290919-A1 | ANTIBODY-DRUG CONJUGATE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| EP-3210623-A1 | ANTIBODY-DRUG COMPLEX HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF Corporation (JP) | 2017-08-30 | — | — | EP | disclosed |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3130587-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF Corporation (JP) | 2017-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, H1-0, H1-3 | CYP1A2 3131/4885CYP2C19 3364/4885CYP2C9 4149/4885 |
| US-11529423-B2 | Biodegradable polyethylene glycol derivative having cyclic benzylidene acetal linker | AMDHD2, PGD, TREH | CYP1A2 2041/4885CYP2C19 853/4885CYP2C9 1979/4885 |
| US-10626217-B2 | Lipid derivative in which hydrophilic polymer is bound through cyclic benzylidene acetal linker | SGMS1, SGMS2, CERT1 | CYP1A2 1420/4885CYP2C19 1921/4885CYP2C9 2772/4885 |
| US-10808050-B2 | Antibody-drug conjugate having cyclic benzylidene acetal linker | H1-2, CD22, H1-0 | CYP1A2 1026/4885CYP2C19 766/4885CYP2C9 1120/4885 |
| US-20180078651-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | AMDHD2, PGD, TREH | CYP1A2 2041/4885CYP2C19 853/4885CYP2C9 1979/4885 |
| US-11041052-B2 | Biodegradable hydrogel having cyclic benzylidene acetal structure | H1-0, H1-2, H1-4 | CYP1A2 1454/4885CYP2C19 1670/4885CYP2C9 1631/4885 |
| US-20170290919-A1 | ANTIBODY-DRUG CONJUGATE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, CD22, H1-0 | CYP1A2 1026/4885CYP2C19 766/4885CYP2C9 1120/4885 |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | H1-2, H1-0, H1-3 | CYP1A2 3131/4885CYP2C19 3364/4885CYP2C9 4149/4885 |
| US-20200289656-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | AMDHD2, PGD, TREH | CYP1A2 2041/4885CYP2C19 853/4885CYP2C9 1979/4885 |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, H1-0, H1-3 | CYP1A2 3117/4885CYP2C19 3310/4885CYP2C9 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.