SCHEMBL1639299

SCHEMBL1639299

CC(=O)c1ccccc1OCC(C)(C)C

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
KDM4E B2RXH2 2/20 0.62
ALDH1A1 P00352 2/20 0.62
MAPT P10636 4/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ABCB1 P08183 4/20 0.49
HTT P42858 2/20 0.48
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20503321 0.86 ALDH1A1 (0.59) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL17859344 0.84 LMNA (0.60) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL26215614 0.81 LMNA (0.41) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL20060388 0.80 MAOB (0.47) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL335970 0.79 LMNA (0.71) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL30292656 0.79 LMNA (0.71) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL16656684 0.79 LMNA (0.68) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL11353397 0.79 ABCB1 (0.42) LMNASMN1; SMN2KDM4EALDH1A1ABCB1
SCHEMBL13449767 0.78 KDM4E (0.41) LMNASMN1; SMN2KDM4EALDH1A1MAPT
SCHEMBL7043647 0.78 LMNA (0.66) LMNASMN1; SMN2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181697-B1 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO CO LTD (JP) 2015-04-22 EP claimed
US-8182795-B2 Oil-in-water emulsion type sunscreen preparation SHISEIDO CO., LTD. (JP) 2012-05-22 US claimed
US-20100209365-A1 Oil-In-Water Emulsion Type Sunscreen Preparation SHISEIDO COMPANY, LTD. (JP) 2010-08-19 US claimed
EP-2181697-A2 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO COMPANY, LTD. (JP) 2010-05-05 EP claimed
CN-115670983-B Sun-screening composition, sun-screening cream containing same and preparation method thereof 广州远想生物科技股份有限公司 2024-03-12 CN disclosed
CN-111329787-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
CN-111329788-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
CN-111481469-A Copolymer 宝丽化学工业有限公司 2020-08-04 CN disclosed
CN-111358713-A Copolymer 宝丽化学工业有限公司 2020-07-03 CN disclosed
CN-111329787-A Copolymer 宝丽化学工业有限公司 2020-06-26 CN disclosed
CN-111329788-A Copolymer 宝丽化学工业有限公司 2020-06-26 CN disclosed
EP-2774602-B1 AQUEOUS DISPERSION AND METHOD FOR PRODUCING SAME FUJIFILM CORP (JP) 2020-06-03 EP disclosed
EP-2181697-A2 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO COMPANY, LTD. (JP) 2010-05-05 EP disclosed
EP-2181697-A2 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO COMPANY, LTD. (JP) 2010-05-05 EP disclosed
EP-2174646-A1 INVERTED VESICLE Kao Corporation (JP) 2010-04-14 EP disclosed
EP-2168568-A1 SKIN COSMETIC Shiseido Company, Limited (JP) 2010-03-31 EP disclosed
US-20090258964-A1 Skin Cosmetic SHISEIDO COMPANY, LTD. (JP) 2009-10-15 US disclosed
WO-2007122822-A3 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO CO LTD (JP) 2008-02-21 WO disclosed
WO-2007122822-A2 OIL-IN-WATER EMULSION TYPE SUNSCREEN PREPARATION SHISEIDO COMPANY, LTD. (JP) 2007-11-01 WO disclosed
JP-2003055149-A SKIN CARE PREPARATION SHISEIDO CO LTD 2003-02-26 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258964-A1 Skin Cosmetic CUTA, DEGS1, ALAD LMNA 1367/4885SMN1; SMN2 4126/4885KDM4E 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.