Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345338 | 0.88 | ALDH1A1 (0.49) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30628273 | 0.82 | CYP3A4 (0.61) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4271221 | 0.82 | CYP3A4 (0.61) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL1639299 | 0.80 | LMNA (0.62) | ALDH1A1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL18329451 | 0.80 | MAOB (0.43) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13637553 | 0.79 | LMNA (0.52) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4200539 | 0.79 | MAOB (0.48) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL3846283 | 0.78 | LMNA (0.51) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL22688804 | 0.78 | MAOB (0.47) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6566562 | 0.78 | LMNA (0.47) | MAOBMAOAALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3309163-A1 | SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE | UBE Industries, Ltd. (JP) | 2018-04-18 | — | — | EP | disclosed |