Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066852 | 0.81 | GPR35 (0.58) | GPR35MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL16395952 | 0.81 | KDM4E (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL17173228 | 0.79 | MCL1 (0.55) | GPR35MAPTMEN1KMT2AMCL1 | |
| SCHEMBL15697527 | 0.76 | G6PD (0.43) | GPR35ALDH1A1KDM4EHPGDCYP2C9 | |
| SCHEMBL11804710 | 0.74 | ALDH1A1 (0.47) | GPR35MAPTALDH1A1KDM4ECYP3A4 | |
| SCHEMBL647033 | 0.74 | MCL1 (0.65) | GPR35MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL16396143 | 0.71 | MMP12 (0.47) | GPR35ALDH1A1HSD17B10PTPN1POLB | |
| SCHEMBL30340804 | 0.70 | MAPT (0.58) | MAPTALDH1A1KDM4ECYP3A4MEN1 | |
| SCHEMBL3887754 | 0.70 | MAPT (0.58) | MAPTALDH1A1KDM4ECYP3A4MEN1 | |
| SCHEMBL16096208 | 0.69 | IKBKB (0.45) | MAPTALDH1A1KDM4EMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004057-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C Research Laboratories (KR) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196793-A1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RESEARCH LABORATORIES (KR) | 2014-12-11 | — | — | WO | disclosed |