SCHEMBL1639728

SCHEMBL1639728

CCO[Si](C)(OCC)c1cccc(-c2ccccc2)c1[Si](C)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
NPC1 O15118 3/20 0.33
KDM4E B2RXH2 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.31
ENPP1 P22413 2/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639792 0.87 KDM4E (0.33) NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639789 0.87
SCHEMBL27599920 0.86 ALDH1A1 (0.37) PDCD1CD274NPC1KDM4ERAB9A
SCHEMBL1639207 0.82 CYP1A2 (0.34) MAPT
SCHEMBL545764 0.79 CD274 (0.35) PDCD1CD274NPC1KDM4ERAB9A
SCHEMBL1639726 0.79 ALDH1A1 (0.34) NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL1639810 0.78 MAPT (0.35) PDCD1CD274NPC1KDM4ERAB9A
SCHEMBL30473468 0.76 ALDH1A1 (0.32) NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL1638005 0.76 ALDH1A1 (0.32) NPC1KDM4ERAB9ASMN1; SMN2ALDH1A1
SCHEMBL4279699 0.74 ADRB2 (0.37) PDCD1CD274NPC1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1391476-B1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO LTD (JP) 2015-12-09 EP disclosed
US-8536242-B2 Photocurable composition SEKISUI CHEMICAL CO., LTD. (JP) 2013-09-17 US disclosed
US-20110097669-A1 PHOTOCURABLE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2011-04-28 US disclosed
US-7312013-B2 Photoreactive composition SEKISUI CHEMICAL CO., LTD. (JP) 2007-12-25 US disclosed
US-20040202956-A1 a photocurable mixture of a hydrolyzable metal (silyl) compound and a reaction, polymerization or crosslinking promoter; curing; adhesives, seals, semiconductors, dielectrics, microlenses, optical fibers, color filters, gas permeable films SEKISUI CHEMICAL CO., LTD. (JP) 2004-10-14 US disclosed
EP-1391476-A1 PHOTOREACTIVE COMPOSITION SEKISUI CHEMICAL CO., LTD. (JP) 2004-02-25 EP disclosed