SCHEMBL1764460

SCHEMBL1764460

Oc1ccc(CCCCn2nnc3ccccc32)cc1.[NaH]

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.60
▸ NPC1 O15118 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ SLC9A1 P19634 8/20 0.58
▸ RPS6KA3 P51812 1/20 0.55
▸ EGLN3 Q9H6Z9 2/20 0.50
▸ TDP1 Q9NUW8 1/20 0.48
▸ GLA P06280 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ GRM2 Q14416 2/20 0.48
▸ PLA2G4A P47712 1/20 0.47
▸ KCNMA1 Q12791 1/20 0.47
▸ P2RX7 Q99572 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3651402 0.99 MAPT (0.61) MAPTNPC1RAB9ASLC9A1RPS6KA3
SCHEMBL16398499 0.79 GRM2 (0.75) MAPTNPC1RAB9ASLC9A1RPS6KA3
SCHEMBL22721204 0.79 MAPT (0.55) MAPTNPC1RAB9ASLC9A1EGLN3
SCHEMBL14796568 0.78 SLC9A1 (0.79) MAPTNPC1RAB9ASLC9A1EGLN3
SCHEMBL7672509 0.77 SLC9A1 (0.71) MAPTNPC1RAB9ASLC9A1EGLN3
SCHEMBL2478499 0.76 RPS6KA3 (0.43) MAPTNPC1RAB9ARPS6KA3TDP1
SCHEMBL7667067 0.76 SLC9A1 (0.70) MAPTNPC1RAB9ASLC9A1RPS6KA3
SCHEMBL3428426 0.76 NPC1 (1.00) MAPTNPC1RAB9ASLC9A1EGLN3
SCHEMBL29482278 0.76 SLC9A1 (0.70) MAPTNPC1RAB9ASLC9A1RPS6KA3
SCHEMBL17103011 0.74 SLC9A1 (0.90) MAPTNPC1RAB9ASLC9A1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2538938-B1 FUNGAL NAIL TREATMENT COMPOSITION LRC PRODUCTS (GB) 2019-04-24 — — EP claimed
EP-2205200-A2 HAIR CARE FORMULATIONS COMPRISING UV-ABSORBERS AND SILICONES BASF SE (DE) 2010-07-14 — — EP claimed
WO-2009043841-A2 HAIR CARE FORMULATIONS COMPRISING UV-ABSORBERS AND SILICONES BASF SE (DE) 2009-04-09 — — WO claimed
CN-121586704-A Adhesive photoprotective compounds and uses thereof 斯奇诺西维 2026-02-27 — — CN disclosed
US-20250177286-A1 COMPOSITIONS FOR SENSITIVE SKIN MARY KAY INC. 2025-06-05 — — US disclosed
US-12233154-B2 Compositions for sensitive skin MARY KAY INC (US) 2025-02-25 — — US disclosed
US-20240207170-A1 COMPOSITIONS FOR SENSITIVE SKIN ALLUSTRA TECHNOLOGIES LLC 2024-06-27 — — US disclosed
US-11865204-B2 Compositions for sensitive skin MARY KAY INC. (US) 2024-01-09 — — US disclosed
EP-3532020-B1 FEMININE HYGIENE PRODUCTS RB HEALTH US LLC (US) 2023-03-29 — — EP disclosed
US-11576880-B2 Feminine hygiene products RB HEALTH (US) LLC (US) 2023-02-14 — — US disclosed
US-20200367492-A1 TREATMENT COMPOSITIONS PROVIDING AN ANTIMICROBIAL BENEFIT RECKITT BENCKISER LLC (US) 2020-11-26 — — US disclosed
WO-2007031756-A1 FOAMING TOPICAL COMPOSITIONS RECKITT BENCKISER INC (US) 2007-03-22 — — WO disclosed
WO-2007031793-A2 IMPROVEMENTS IN OR RELATIMG TO COSMETIC COMPOSITIONS RECKITT BENCKISER (UK) LIMITED (GB) 2007-03-22 — — WO disclosed
US-7166137-B2 Methods, compositions, and kits for coloring hair REVLON CONSUMER PRODUCTS CORPORATION (US) 2007-01-23 — — US disclosed
WO-2006117516-A2 TOPICAL COMPOSITIONS RECKITT BENCKISER INC (US) 2006-11-09 — — WO disclosed
US-20050097684-A1 Methods, compositions, and kits for coloring hair MUFG BANK LTD. AS AGENT 2005-05-12 — — US disclosed
US-20050069517-A1 Hair conditioning compositions NEUTROGENA CORPORATION 2005-03-31 — — US disclosed
US-20050069516-A1 Hair conditioning products NEUTROGENA CORPORATION 2005-03-31 — — US disclosed
US-6669933-B2 For oxidatively coloring hair in twelve minutes or less REVLON CONSUMER PRODUCTS CORPORATION 2003-12-30 — — US disclosed
WO-2002089748-A2 METHOD AND COMPOSITIONS FOR COLORING HAIR REVLON CONSUMER PRODUCTS CORPORATION (US) 2002-11-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11576880-B2 Feminine hygiene products LDHA, TES, LDHB MAPT 3962/4885NPC1 4885/4885RAB9A 4358/4885
US-20200367492-A1 TREATMENT COMPOSITIONS PROVIDING AN ANTIMICROBIAL BENEFIT CUTA, DSG1, SGMS1 MAPT 2659/4885NPC1 1290/4885RAB9A 2953/4885
US-20050097684-A1 Methods, compositions, and kits for coloring hair COXFA4L2, COX5B, COX5A MAPT 2524/4885NPC1 4829/4885RAB9A 4634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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