Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 8/20 | 0.65 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398499 | 0.80 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4ELMNA | |
| SCHEMBL2734889 | 0.80 | GRM2 (1.00) | GRM2SLC9A1TDP1KDM4EKCNMA1 | |
| SCHEMBL22000732 | 0.77 | GRM2 (0.75) | GRM2SLC9A1TDP1LMNAKCNMA1 | |
| SCHEMBL28345673 | 0.77 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EKCNMA1 | |
| SCHEMBL7597659 | 0.77 | GRM2 (0.75) | GRM2SLC9A1TDP1KDM4EPTK2 | |
| SCHEMBL16104116 | 0.77 | PTK2 (0.73) | GRM2SLC9A1TDP1PTK2 | |
| SCHEMBL2800642 | 0.77 | SLC9A1 (0.58) | GRM2SLC9A1KDM4EKCNMA1EGLN3 | |
| SCHEMBL14376781 | 0.75 | GRM2 (0.61) | GRM2SLC9A1TDP1KDM4ELMNA | |
| SCHEMBL22058723 | 0.74 | GRM2 (0.65) | GRM2SLC9A1TDP1KDM4ELMNA | |
| SCHEMBL3460030 | 0.74 | EGLN3 (0.62) | GRM2SLC9A1KDM4ELMNAKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026092-B | Guanidine-substituted imidazo [4,5-c ] ring compounds | 3M创新有限公司 | 2021-01-26 | — | — | CN | disclosed |