SCHEMBL16400396

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16400397	1.00	MAOB (0.41)	MAOBNFE2L2KDM4ENPC1HPGD
	SCHEMBL18004333	0.91	NFE2L2 (0.37)	MAOBNFE2L2KDM4ECHRNB2CHRNB4
	SCHEMBL18004418	0.91	CYP1A1 (0.34)	KDM4ENPC1HPGDRAB9ASMN1; SMN2
	SCHEMBL16398801	0.90	CHRNB2 (0.40)	MAOBNFE2L2KDM4ESMN1; SMN2NPSR1
	SCHEMBL16398798	0.90	CHRNB2 (0.40)	MAOBNFE2L2KDM4ESMN1; SMN2NPSR1
	SCHEMBL18004824	0.90	NFE2L2 (0.42)	MAOBNFE2L2NPSR1CHRNB2CHRNB4
	SCHEMBL18004498	0.89	CYP1A1 (0.38)	MAOBKDM4ENPC1HPGDRAB9A
	SCHEMBL16399763	0.89	NFE2L2 (0.41)	MAOBNFE2L2KDM4ECHRNB2CHRNB4
	SCHEMBL16399761	0.89	NFE2L2 (0.41)	MAOBNFE2L2KDM4ECHRNB2CHRNB4
	SCHEMBL18004461	0.89	NFE2L2 (0.35)	MAOBNFE2L2SMN1; SMN2NPSR1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.