SCHEMBL16401062

SCHEMBL16401062

O=P(Oc1cccc2cccnc12)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.52
METAP2 P50579 2/20 0.52
METAP1 P53582 2/20 0.52
HDAC6 Q9UBN7 1/20 0.52
RAB9A P51151 5/20 0.51
MAPT P10636 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.50
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HSP90AA1 P07900 1/20 0.49
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
POLB P06746 1/20 0.46
ALDH1A1 P00352 2/20 0.46
GLRA3 O75311 1/20 0.45
GLRB P48167 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664206 0.82 KDM4E (0.53) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL7261599 0.79 MAPT (0.54) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL722399 0.79 KDM4E (0.50) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL29100487 0.79 MAPT (0.54) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL4461219 0.79 SRC (0.57) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL4381777 0.79 LMNA (0.50) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL28128326 0.76 MAPT (0.51) LMNAMETAP2METAP1HDAC6RAB9A
SCHEMBL38658410 0.76 CCR1 (0.47) LMNARAB9AMAPTL3MBTL1SMN1; SMN2
SCHEMBL30544121 0.75 ALDH1A1 (0.50) LMNAMAPTL3MBTL1SMN1; SMN2KDM4E
SCHEMBL3473759 0.75 HTT (0.48) LMNARAB9AL3MBTL1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10879473-B2 Organic electronic device NOVALED GMBH (DE) 2020-12-29 US disclosed
US-10879473-B2 Organic electronic device NOVALED GMBH (DE) 2020-12-29 US disclosed
US-20160118603-A1 Organic Electronic Device NOVALED GMBH (DE) 2016-04-28 US disclosed
US-20160118603-A1 Organic Electronic Device NOVALED GMBH (DE) 2016-04-28 US disclosed
US-20160118603-A1 Organic Electronic Device NOVALED GMBH (DE) 2016-04-28 US disclosed
WO-2014195482-A2 ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2014-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10879473-B2 Organic electronic device OR10J3, LAGE3, L1CAM LMNA 1671/4885METAP2 3024/4885METAP1 3709/4885
US-20160118603-A1 Organic Electronic Device OR10J3, LAGE3, L1CAM LMNA 1671/4885METAP2 3024/4885METAP1 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.