Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403960 | 0.94 | SCD (0.42) | SCDMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL16403957 | 0.90 | HSD17B10 (0.52) | SCDROCK2 | |
| SCHEMBL16403934 | 0.87 | TRPV1 (0.40) | MAPTALDH1A1GAAROCK2TRPV1 | |
| SCHEMBL16404086 | 0.86 | SCD (0.42) | SCDSMN1; SMN2TRPV1 | |
| SCHEMBL16403958 | 0.85 | HCRTR1 (0.48) | SCDROCK2 | |
| SCHEMBL16403937 | 0.84 | NPC1 (0.47) | SCDMAPTSMN1; SMN2ALDH1A1ROCK2 | |
| SCHEMBL16403930 | 0.83 | NPC1 (0.49) | SCDSMN1; SMN2ALDH1A1ROCK2 | |
| SCHEMBL16404158 | 0.73 | NPC1 (0.50) | MAPTSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL16403918 | 0.72 | NPC1 (0.47) | MAPTSMN1; SMN2HTTALDH1A1GAA | |
| SCHEMBL16403992 | 0.72 | RAB9A (0.60) | SMN1; SMN2HTTALDH1A1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |