Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16403916 | 0.87 | ALDH1A1 (0.48) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403918 | 0.86 | NPC1 (0.47) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403979 | 0.83 | MGLL (0.48) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL14684758 | 0.80 | LMNA (0.53) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16404113 | 0.79 | CCNC (0.55) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403981 | 0.77 | RAB9A (0.43) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403980 | 0.77 | KDM4E (0.44) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL14318276 | 0.77 | ATP4A (0.69) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403985 | 0.77 | RAB9A (0.41) | RAB9AALDH1A1NPC1PKMHPGD | |
| SCHEMBL16403966 | 0.77 | LMNA (0.55) | ALDH1A1NPSR1LMNASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |