Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 11/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404086 | 0.93 | SCD (0.42) | HCRTR1GRM5HCRTR2SCD5SCD | |
| SCHEMBL16403957 | 0.88 | HSD17B10 (0.52) | HCRTR1HCRTR2SCD5SCDROCK2 | |
| SCHEMBL16403934 | 0.87 | TRPV1 (0.40) | HCRTR1GRM5HCRTR2SCD5ROCK2 | |
| SCHEMBL16404125 | 0.85 | SCD (0.47) | SCDROCK2 | |
| SCHEMBL16403960 | 0.84 | SCD (0.42) | HCRTR1HCRTR2SCD5SCDROCK2 | |
| SCHEMBL16403937 | 0.76 | NPC1 (0.47) | HCRTR1HCRTR2SCD5SCDROCK2 | |
| SCHEMBL16403930 | 0.75 | NPC1 (0.49) | SCD5SCDROCK2 | |
| SCHEMBL16403918 | 0.71 | NPC1 (0.47) | ROCK2 | |
| SCHEMBL16403992 | 0.71 | RAB9A (0.60) | — | |
| SCHEMBL16403916 | 0.70 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937065-B2 | Compositions and methods for modulating a kinase | CLEVEXEL PHARMA (FR) | 2015-01-20 | — | — | US | disclosed |