SCHEMBL16406554

SCHEMBL16406554

CC(CC(C)C(=O)N(C)C)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ELANE P08246 10/20 0.61
ABCB1 P08183 1/20 0.44
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
PKM P14618 1/20 0.43
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ESRRB O95718 1/20 0.42
ACHE P22303 1/20 0.42
NPC1 O15118 2/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
GAA P10253 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL825544 0.80 ELANE (0.71) ELANEABCB1KMT2AALDH1A1LMNA
SCHEMBL19862709 0.79 ELANE (0.61) ELANEABCB1KMT2AALDH1A1LMNA
SCHEMBL11861904 0.78 ELANE (0.51) ELANEKMT2AALDH1A1LMNAL3MBTL1
SCHEMBL10483706 0.77 ELANE (1.00) ELANEKMT2AALDH1A1NPC1HPGD
SCHEMBL26311013 0.76 ATM (0.39) ELANEKMT2AALDH1A1PKML3MBTL1
SCHEMBL19862713 0.74 ELANE (0.54) ELANEKMT2AALDH1A1L3MBTL1RAB9A
SCHEMBL19862712 0.74 ELANE (0.54) ELANEABCB1KMT2AALDH1A1LMNA
SCHEMBL669562 0.74 ELANE (0.76) ELANEKMT2AALDH1A1NPC1GAA
SCHEMBL19862711 0.73 ELANE (0.53) ELANEKMT2AALDH1A1LMNAL3MBTL1
SCHEMBL2296618 0.72 ELANE (0.49) ELANEKMT2AALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150025168-A1 SYNTHESIS AND MICRO-/NANOSTRUCTURING OF SURFACE-ATTACHED CROSSLINKED ANTIMICROBIAL AND/OR ANTIBIOFOULING POLYMER NETWORKS UNIVERSITATSKLINIKUM FREIBURG (DE) 2015-01-22 US disclosed