Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 11/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410536 | 0.75 | TSHR (0.35) | MEN1KMT2A | |
| SCHEMBL17757206 | 0.73 | EPHX2 (0.39) | EPHX2MEN1KMT2A | |
| SCHEMBL19523208 | 0.64 | GNAI3 (0.41) | GNAI3GNAI1GSK3BMEN1KMT2A | |
| SCHEMBL14301937 | 0.64 | HTR7 (0.59) | MEN1KMT2A | |
| SCHEMBL2131896 | 0.62 | ALDH1A1 (0.60) | MEN1KMT2A | |
| SCHEMBL2703912 | 0.62 | ALDH1A1 (0.48) | ARMEN1KMT2A | |
| SCHEMBL3455760 | 0.61 | CA12 (0.51) | MEN1KMT2A | |
| SCHEMBL10527238 | 0.61 | TET3 (0.49) | EPHX2KMT2A | |
| Bromide SCHEMBL4302260 | 0.61 | SIGMAR1 (0.62) | MEN1KMT2A | |
| SCHEMBL13302257 | 0.61 | LMNA (0.49) | EPHX2GNAI3GNAI1ARMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007730-A1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2015-01-22 | — | — | WO | disclosed |