Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468871 | 0.86 | SGMS2 (0.67) | LMNASMN1; SMN2ALDH1A1KDM4EMAOB | |
| SCHEMBL71081 | 0.86 | SGMS2 (0.67) | LMNASMN1; SMN2ALDH1A1KDM4EMAOB | |
| SCHEMBL3135517 | 0.84 | LMNA (0.74) | LMNASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| Lithium SCHEMBL385607 | 0.83 | LMNA (0.72) | LMNASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL385606 | 0.83 | LMNA (0.72) | LMNASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL15887756 | 0.81 | MEN1 (0.62) | LMNASMN1; SMN2ALDH1A1KDM4EMAOB | |
| SCHEMBL10102482 | 0.79 | RXRA (0.68) | LMNASMN1; SMN2ALDH1A1KDM4EMAOB | |
| SCHEMBL13348916 | 0.78 | MRGPRX4 (0.71) | SMN1; SMN2MEN1KMT2ANPC1MRGPRX4 | |
| SCHEMBL11421173 | 0.78 | ALDH1A1 (0.65) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15922822 | 0.78 | HTR1A (0.65) | ALDH1A1KDM4EL3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611819-A1 | IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | Takasago International Corporation (JP) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012029970-A1 | IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-03-08 | — | — | WO | disclosed |