Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10809737 | 1.00 | CYP3A4 (0.41) | CYP3A4MAPTDRD2DRD3ADRA1A | |
| Hydrochloric Acid SCHEMBL10808561 | 0.98 | DRD2 (0.40) | CYP3A4MAPTDRD2DRD3ADRA1A | |
| SCHEMBL16428194 | 0.79 | EP300 (0.42) | CYP3A4MAPTEP300CA1CA2 | |
| SCHEMBL16428197 | 0.79 | EP300 (0.42) | CYP3A4MAPTEP300CA1CA2 | |
| SCHEMBL3041826 | 0.77 | ADRA1A (0.56) | CYP3A4MAPTDRD2DRD3ADRA1A | |
| SCHEMBL10809253 | 0.77 | ALDH1A1 (0.44) | CYP3A4MAPTDRD2DRD3EP300 | |
| Hydrochloric Acid SCHEMBL10813428 | 0.76 | DRD2 (0.53) | DRD2DRD3CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10815321 | 0.76 | DRD2 (0.53) | DRD2DRD3ACHE | |
| Hydrochloric Acid SCHEMBL10808479 | 0.76 | ALDH1A1 (0.43) | CYP3A4MAPTDRD2DRD3EP300 | |
| Hydrochloric Acid SCHEMBL1788805 | 0.75 | ADRA1A (0.54) | CYP3A4MAPTDRD2DRD3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163038-B2 | Process for synthesis of chiral 3-substituted tetrahydroquinoline derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-10-20 | — | — | US | disclosed |
| US-20150038714-A1 | Process for Synthesis of Chiral 3-Substituted Tetrahydroquinoline Derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038714-A1 | Process for Synthesis of Chiral 3-Substituted Tetrahydroquinoline Derivatives | TH, DHPS, QDPR | CYP3A4 107/4885MAPT 3402/4885DRD2 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.