SCHEMBL16429081

SCHEMBL16429081

CC(C)CNCCCNC(CCN)Cc1cc(CC(CCN)NCCCNCC(C)C)cc(OCc2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ RRM1 P23921 1/20 0.42
▸ SIGMAR1 Q99720 3/20 0.42
▸ EPOR P19235 2/20 0.41
▸ BCHE P06276 7/20 0.39
▸ ALDH1A1 P00352 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16429307 0.87 RRM1 (0.43) MEN1KMT2ASMN1; SMN2RAB9ARRM1
SCHEMBL16247109 0.84 SIGMAR1 (0.40) MEN1KMT2ASIGMAR1KDM4E
SCHEMBL16246958 0.84 CARM1 (0.34) MEN1KMT2ASMN1; SMN2RAB9ASIGMAR1
SCHEMBL16428818 0.84 SIGMAR1 (0.39) MEN1KMT2ASIGMAR1
SCHEMBL16428995 0.82 — —
SCHEMBL16429080 0.82 MEN1 (0.46) MEN1KMT2ASMN1; SMN2RAB9ARRM1
SCHEMBL16264653 0.81 BCHE (0.55) MEN1KMT2ASMN1; SMN2RAB9ABCHE
SCHEMBL18223041 0.81 SIGMAR1 (0.36) MEN1KMT2ASIGMAR1
SCHEMBL16429452 0.80 CNR1 (0.39) KMT2ASIGMAR1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29778267 0.80 BCHE (0.54) MEN1KMT2ASMN1; SMN2RAB9ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10440955-B2 Methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2019-10-15 — — US disclosed
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2018-05-10 — — US disclosed
US-9839219-B2 Compositions comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2017-12-12 — — US disclosed
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE CURZA GLOBAL, LLC 2016-11-17 — — US disclosed
US-9439433-B2 Compositions and methods comprising a biocidal polyamine CURZA GLOBAL, LLC (US) 2016-09-13 — — US disclosed
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE THE UNIVERSITY OF UTAH 2015-02-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160330962-A1 COMPOSITIONS COMPRISING A BIOCIDAL POLYAMINE SRM, SMS, SMOX MEN1 1109/4885KMT2A 2137/4885SMN1; SMN2 4729/4885
US-10440955-B2 Methods comprising a biocidal polyamine SRM, SMOX, SMS MEN1 1586/4885KMT2A 2076/4885SMN1; SMN2 4734/4885
US-20180125070-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS MEN1 1222/4885KMT2A 1888/4885SMN1; SMN2 4731/4885
US-20150038512-A1 COMPOSITIONS AND METHODS COMPRISING A BIOCIDAL POLYAMINE SRM, SMOX, SMS MEN1 1222/4885KMT2A 1888/4885SMN1; SMN2 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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