Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL286882 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2446607 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL678415 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL362235 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1866839 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL7759526 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL635580 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL8775234 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2979400 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1963378 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 562 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118209650-A | Method for extracting and determining succinate dehydrogenase inhibitor based on magnetic eutectic solvent-liquid microextraction-high performance liquid chromatography | 山西农业大学 | 2024-06-18 | — | — | CN | claimed |
| CN-111944005-B | Cholic acid-hexyl-triphenyl phosphonium bromide and preparation method and application thereof | 首都医科大学 | 2023-04-18 | — | — | CN | claimed |
| CN-115417769-A | Method for synthesizing sex pheromone component of tomato leaf miner and intermediate | 昆明博鸿科技有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-115337297-A | CPI-613 mitochondrion targeted small molecule prodrug, self-assembled nanoparticles thereof, preparation method and application | 沈阳药科大学 | 2022-11-15 | — | — | CN | claimed |
| CN-114318853-A | Modified antibacterial fiber | 安徽润齐新材料科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-113278086-A | Antibacterial material of quaternary phosphonium salt modified locust bean gum | 广州市尚信净化工程有限公司 | 2021-08-20 | — | — | CN | claimed |
| EP-2069452-B1 | ONIUM-CONTAINING CMP COMPOSITIONS AND METHODS OF USE THEREOF | CABOT MICROELECTRONICS CORP (US) | 2016-11-09 | — | — | EP | claimed |
| US-20160297829-A1 | METHOD FOR PRODUCING AVENACIOLIDES AND USES THEREOF | ACADEMIA SINICA (TW) | 2016-10-13 | — | — | US | claimed |
| US-9129907-B2 | Onium-containing CMP compositions and methods of use thereof | CABOT MICROELECTRONICS CORPORATION (US) | 2015-09-08 | — | — | US | claimed |
| EP-1973974-B1 | A PROCESS FOR PREPARING 'ONIUM SALTS | SUN CHEMICAL CORP (US) | 2014-04-30 | — | — | EP | claimed |
| US-6086661-A | (A)IMIDAZOLINIUM QUATERNARY SALT, (B) PHOSPHONIUM QUATERNARY SALT, OR (C) AN AMMONIUM QUATERNARY SALT; A PAPER-CURL REDUCING COMPOUND; DYE; STABILIZERS, BIOCIDE, WATER SOLUBLE SALT | XEROX CORPORATION (US) | 2000-07-11 | — | — | US | claimed |
| US-5760809-A | INK JET PRINTING | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| US-5709976-A | Coated papers | XEROX CORPORATION (US) | 1998-01-20 | — | — | US | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0615853-B1 | Recording sheets containing phosphonium compounds | XEROX CORP (US) | 1996-10-16 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| EP-0615853-A1 | Recording sheets containing phosphonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| US-4532274-A | Also containing polyol, hardener, catalyst, aluminum trihydrate | UNION CARBIDE CORPORATION (US) | 1985-07-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297829-A1 | METHOD FOR PRODUCING AVENACIOLIDES AND USES THEREOF | COASY, ERG28, GSK3B | HIF1A 4070/4885TRAP1 2409/4885CHRNA7 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.