Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL286882 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2446607 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL678415 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL362235 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1866839 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL7759526 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL635580 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL8775234 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL164301 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1963378 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119411242-A | Comfortable quick-response antibacterial and antiviral fiber and preparation method thereof | 上海德福伦新材料科技有限公司 | 2025-02-11 | — | — | CN | claimed |
| CN-116948547-A | Novel white reinforced photovoltaic backboard base film, preparation method and application thereof | 宁波勤邦新材料科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115536997-A | Blending type barrier plastic packaging container | 杭州恒峰塑料制品有限公司 | 2022-12-30 | — | — | CN | claimed |
| WO-2009002778-A1 | ADDITIVES TO IMPROVE HIGH TEMPERATURE PERFORMANCE OF POLYESTERS | ARKEMA INC. (US) | 2008-12-31 | — | — | WO | claimed |
| EP-3710462-B1 | BRARTEMICIN ANALOGUES | VICTORIA LINK LTD (NZ) | 2026-05-13 | — | — | EP | disclosed |
| US-12577264-B2 | Borate compound-containing composition | AGC Inc. (JP) | 2026-03-17 | — | — | US | disclosed |
| CN-119411242-A | Comfortable quick-response antibacterial and antiviral fiber and preparation method thereof | 上海德福伦新材料科技有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-116948547-B | White reinforced photovoltaic backboard base film, preparation method and application thereof | 宁波勤邦新材料科技股份有限公司 | 2024-09-17 | — | — | CN | disclosed |
| WO-2024105547-A1 | 6-C-LINKED TREHALOSE GLYCOLIPIDS | VICTORIA LINK LIMITED (NZ) | 2024-05-23 | — | — | WO | disclosed |
| EP-4274834-A1 | ISOHEXANE-SOLUBLE UNSATURATED ALKYL ANILINIUM TETRAKIS(PERFLUOROARYL)BORATE ACTIVATORS | ExxonMobil Chemical Patents Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116948547-A | Novel white reinforced photovoltaic backboard base film, preparation method and application thereof | 宁波勤邦新材料科技股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4265623-A1 | NOVEL BORATE COMPOUND | AGC INC. (JP) | 2023-10-25 | — | — | EP | disclosed |
| WO-2005047221-A1 | PROCESS FOR THE PREPARATION OF ALIPHATIC PRIMARY ALCOHOLS AND INTERMEDIATES IN SUCH PROCESS | DSM IP ASSETS B.V. (NL) | 2005-05-26 | — | — | WO | disclosed |
| US-5446189-A | Diester intermediates for diacid enzyme inhibitor | HOFFMANN-LA ROCHE INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5324747-A | Treatment of inflammatory diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0579066-A2 | N-substituted anilines | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| EP-0109354-A1 | Biocidally active mixture | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |
| EP-0097890-A2 | Process for producing an aromatic polyester | MITSUBISHI KASEI CORPORATION (JP) | 1984-01-11 | — | — | EP | disclosed |
| US-4035346-A | ANTISTATIC | E. I. DU PONT DE NEMOURS AND CO. (US) | 1977-07-12 | — | — | US | disclosed |
| US-4006123-A | Conductive aliphatic polyester or polyetherester having units containing phosphonium sulfonate groups | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12577264-B2 | Borate compound-containing composition | AFF1, RFC1, RFC3 | HIF1A 2027/4885TRAP1 4691/4885CHRNA7 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.