Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL286882 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2446607 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL678415 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL362235 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1866839 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL7759526 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL8775234 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL164301 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2979400 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1963378 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115888674-A | Uranium adsorption material and preparation method and application thereof | 核工业北京化工冶金研究院 | 2023-04-04 | — | — | CN | claimed |
| CN-114318853-A | Modified antibacterial fiber | 安徽润齐新材料科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-113278086-A | Antibacterial material of quaternary phosphonium salt modified locust bean gum | 广州市尚信净化工程有限公司 | 2021-08-20 | — | — | CN | claimed |
| CN-109734599-A | The synthetic method of one kind (Z/E) -8- dodecylene -1- alcohol acetate compound | 山东省农药科学研究院 | 2019-05-10 | — | — | CN | claimed |
| US-6316575-B1 | MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | claimed |
| EP-0401589-B1 | Method of producing imide bond-containing resins | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 1994-10-26 | — | — | EP | claimed |
| US-5086114-A | Reacting anhydride-containing copolymer with diisocyanate and halogenated phthalic anhydride in the prense of quaternary phosphonium compound | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1992-02-04 | — | — | US | claimed |
| WO-2024261685-A1 | HARDENING COMPOSITION BASED ON RENEWABLE RAW MATERIALS | ECOPOX GMBH & CO. KG (DE) | 2024-12-26 | — | — | WO | disclosed |
| EP-4480983-A1 | CURING COMPOSITION BASED ON RENEWABLE RAW MATERIALS | ECOPOX GmbH & Co. KG (DE) | 2024-12-25 | — | — | EP | disclosed |
| CN-115888674-B | Uranium adsorption material, preparation method and application thereof | 核工业北京化工冶金研究院 | 2024-12-20 | — | — | CN | disclosed |
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) | 2024-09-12 | — | — | US | disclosed |
| WO-2024146848-A1 | CURABLE MATERIALS BASED ON CYCLIC THIOETHER COMPOUNDS, AND USES THEREOF | DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) | 2024-07-11 | — | — | WO | disclosed |
| EP-4357351-A1 | TRAP1 INHIBITOR AND USE THEREOF | Smartin Bio Inc. (KR) | 2024-04-24 | — | — | EP | disclosed |
| US-4391827-A | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor | PFIZER INC. (US) | 1983-07-05 | — | — | US | disclosed |
| US-4376786-A | Combating arthropods with 4-fluoro-3-phenoxy-benzyl 3-alken-1-yl-2,2-dimethyl-cyclopropanecarboxylates | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | disclosed |
| EP-0061053-A1 | 3-Alkene-1-yl-2,2-dimethyl-cyclopropanecarboxylic acid 4-fluoro-3-phenoxy-benzylesters, process for their preparation and their use in pesticides | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| US-4306097-A | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |
| EP-0003294-B1 | USE OF AROMATIC POLYESTERS FOR OPTICAL LENSES | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
| US-4225698-A | HIGH QUALITY LENSES FOR STILL AND MOVIE CAMERAS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| EP-0003294-A1 | Use of aromatic polyesters for optical lenses | BAYER AG (DE) | 1979-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | TRAP1, PPP1R7, PPP1R15A | HIF1A 4001/4885TRAP1 1/4885CHRNA7 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.