Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2446607 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL678415 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL362235 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1866839 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL7759526 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL635580 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL8775234 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL164301 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL2979400 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 | |
| Bromide SCHEMBL1963378 | 1.00 | HIF1A (0.56) | HIF1ATRAP1CHRNA7ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118209650-A | Method for extracting and determining succinate dehydrogenase inhibitor based on magnetic eutectic solvent-liquid microextraction-high performance liquid chromatography | 山西农业大学 | 2024-06-18 | — | — | CN | claimed |
| CN-118019801-A | Fluoropolymer compositions and methods of making the same | 阿科玛股份有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-11428444-B2 | Electrocaloric heat transfer system | CARRIER CORPORATION (US) | 2022-08-30 | — | — | US | claimed |
| EP-1973974-B1 | A PROCESS FOR PREPARING 'ONIUM SALTS | SUN CHEMICAL CORP (US) | 2014-04-30 | — | — | EP | claimed |
| US-7863459-B2 | Process for preparing onium salts | SUN CHEMICAL CORPORATION (US) | 2011-01-04 | — | — | US | claimed |
| US-20080287686-A1 | Process for Preparing Onium Salts | SUN CHEMICAL CORP (US) | 2008-11-20 | — | — | US | claimed |
| EP-1973974-A2 | A PROCESS FOR PREPARING 'ONIUM SALTS | Sun Chemical Corporation (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007075498-A2 | A PROCESS FOR PREPARING 'ONIUM SALTS | SUN CHEMICAL CORPORATION (US) | 2007-07-05 | — | — | WO | claimed |
| EP-0877298-B1 | Coated xerographic photographic paper | XEROX CORP (US) | 2001-08-29 | — | — | EP | claimed |
| US-5908723-A | Recording sheets | XEROX CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| EP-0056679-B1 | ETHANOL SYNTHESIS BY HOMOLOGATION OF METHANOL | TEXACO DEVELOPMENT CORPORATION (US) | 1985-04-17 | — | — | EP | claimed |
| US-4451679-A | RUTHENIUM COMPOUNDS, PHOSPHONIUM OR QUATERNARY AMMONIUM COMPOUNDS | TEXACO INC. (US) | 1984-05-29 | — | — | US | claimed |
| US-4433176-A | CONTAINING RUTHENIUM, COBALT AND RHODIUM COMPOUND AND ONIUM SALT | TEXACO INC. (US) | 1984-02-21 | — | — | US | claimed |
| US-4433178-A | RUTHENIUM, COBALT CONTAINING COMPOUND, AND ONIUM SALT | TEXACO, INC. (US) | 1984-02-21 | — | — | US | claimed |
| US-4433177-A | CONTAINING RUTHENIUM, COBALT COMPOUND, AN AMINE AND ONIUM SALT | TEXACO INC. (US) | 1984-02-21 | — | — | US | claimed |
| US-4414410-A | COBALT, RUTHENIUM AND PHOSPHONIUM COMPOUNDS AS CATALYSTS | TEXACO INC. (US) | 1983-11-08 | — | — | US | claimed |
| US-4374285-A | USING CARBON MONOXIDE AND HYDROGEN AND A CATALYST SYSTEM OF A RUTHENIUM COMPOUND, A QUATERNARY BASE AND A COBALT HALIDE | TEXACO INC. (US) | 1983-02-15 | — | — | US | claimed |
| US-4371724-A | Ethanol synthesis by homologation of methanol | TEXACO INC. (US) | 1983-02-01 | — | — | US | claimed |
| EP-0056679-A1 | Ethanol synthesis by homologation of methanol | TEXACO DEVELOPMENT CORPORATION (US) | 1982-07-28 | — | — | EP | claimed |
| US-4270015-A | CATALYTIC ESTERIFICATION OF AN ACYCLIC ACID USING A COMPLEX OF A RUTHENIUM COMPOUND AND A CESIUM, QUATERNARY AMMONIUM, OR PHOSPHONIUM COMPOUND; PYROLYSIS | TEXACO INC. (US) | 1981-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287686-A1 | Process for Preparing Onium Salts | IK, NOTUM, NOS2 | HIF1A 4488/4885TRAP1 4767/4885CHRNA7 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.