Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205080 | 0.83 | VNN1 (0.38) | PDK2CCR5L3MBTL3 | |
| SCHEMBL3934037 | 0.83 | CCR5 (0.35) | PDK2ALDH1A1CCR5HRH3L3MBTL3 | |
| SCHEMBL17589228 | 0.81 | DPP4 (0.36) | PDK2ALDH1A1CCR5HSD11B1L3MBTL3 | |
| SCHEMBL17589231 | 0.81 | PDK2 (0.33) | PDK2ALDH1A1CCR5L3MBTL3ATM | |
| SCHEMBL10205061 | 0.80 | VNN1 (0.40) | PDK2CCR5HSD11B1KCNH2 | |
| SCHEMBL27926085 | 0.80 | HSD11B1 (0.34) | PDK2ALDH1A1HSD11B1 | |
| SCHEMBL17589227 | 0.79 | CCR5 (0.38) | PDK2CCR5HSD11B1L3MBTL3NPY5R | |
| SCHEMBL16219518 | 0.79 | PDK2 (0.36) | PDK2CCR5L3MBTL3KCNH2 | |
| SCHEMBL10205070 | 0.79 | CCR5 (0.39) | ALDH1A1CCR5HSD11B1KCNH2DRD2 | |
| SCHEMBL16439286 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027610-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - Portela & Cª S.A. (PT) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015016728-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015016729-A1 | UREA COMPOUNDS AND THEIR USE AS FAAH ENZYME INHIBITORS | BIAL - PORTELA & Cª, S.A. (PT) | 2015-02-05 | — | — | WO | disclosed |