Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15132544 | 0.94 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL2825081 | 0.94 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL29971139 | 0.94 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL4463559 | 0.91 | ESR1 (0.41) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL12621158 | 0.89 | NPC1 (0.39) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL15132545 | 0.88 | GPR3 (0.44) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL16502179 | 0.88 | GPR3 (0.44) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL16502181 | 0.88 | PTGS2 (0.55) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL12311636 | 0.88 | HTR2A (0.44) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL16502180 | 0.84 | SMN1; SMN2 (0.46) | NPC1GAANFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419489-B1 | ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2017-08-09 | — | — | EP | disclosed |
| EP-2326695-B1 | BLUE-LIGHT EMITTING MATERIAL | CAMBRIDGE DISPLAY TECH LTD (GB) | 2015-02-25 | — | — | EP | disclosed |
| US-20120085994-A1 | Organic Light-Emitting Materials and Devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2012-04-12 | — | — | US | disclosed |
| US-20110210322-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-01 | — | — | US | disclosed |
| US-20110186828-A1 | Blue light-Emitting Material | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2011-08-04 | — | — | US | disclosed |
| EP-2336215-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | Sumitomo Chemical Company, Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20110124808-A1 | POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2298828-A1 | POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME | Sumitomo Chemical Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010119276-A1 | ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110186828-A1 | Blue light-Emitting Material | CRY1, CRY2, MAP1LC3A | NPC1 4358/4885GAA 3322/4885NFKB1 3416/4885 |
| US-20110124808-A1 | POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME | ZRANB2, ZKSCAN2, SLC39A3 | NPC1 4530/4885GAA 4060/4885NFKB1 1999/4885 |
| US-20110210322-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | H1-10, RNF10, F10 | NPC1 2235/4885GAA 4767/4885NFKB1 1333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.