Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919137 | 0.91 | TDP1 (0.76) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| SCHEMBL10916760 | 0.91 | TDP1 (0.76) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| SCHEMBL11011885 | 0.90 | TDP1 (0.75) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL9754126 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL149538 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL16473046 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL9754124 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL11095123 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL6019446 | 0.90 | TDP1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 | |
| Cefotiam SCHEMBL10899868 | 0.89 | L3MBTL1 (1.00) | TDP1LMNAHSD17B10L3MBTL1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084735-B2 | Self-assembling bis-urea compounds for drug delivery | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-07-21 | — | — | US | disclosed |
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150037390-A1 | SELF-ASSEMBLING BIS-UREA COMPOUNDS FOR DRUG DELIVERY | SLC14A1, NONO, PUF60 | TDP1 2748/4885LMNA 1379/4885HSD17B10 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.