Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639353 | 0.91 | SCN9A (0.47) | MGAMGAASIMGAM2SCN9A | |
| SCHEMBL12726014 | 0.89 | PTGER1 (0.43) | NR1H4MGAMGAASIMGAM2 | |
| SCHEMBL1644133 | 0.89 | NR1H4 (0.42) | NR1H4MGAMGAASIMGAM2 | |
| SCHEMBL1642763 | 0.88 | NR1H4 (0.52) | NR1H4MGAMGAASIMGAM2 | |
| SCHEMBL27864148 | 0.85 | MAOB (0.49) | MGAMGAASIMGAM2PTGER1 | |
| SCHEMBL1637711 | 0.84 | PTGER1 (0.48) | MGAMGAASIMGAM2SCN9A | |
| SCHEMBL12676024 | 0.82 | NR1H4 (0.44) | NR1H4GAAKDM4EL3MBTL1HTT | |
| SCHEMBL1637564 | 0.82 | ADORA3 (0.44) | PTGER1KDM4EL3MBTL1LMNAHPGD | |
| SCHEMBL8409192 | 0.81 | LMNA (0.55) | NR1H4GAASCN9APTGER1KDM4E | |
| SCHEMBL1639034 | 0.80 | MAOB (0.50) | NR1H4SCN9APTGER1MAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557936-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-8557936-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-15 | — | — | US | disclosed |
| CN-102753584-A | Catalyst compounds and use thereof | EXXONMOBIL CHEM PATENTS INC | 2012-10-24 | — | — | CN | disclosed |
| CN-102666597-A | Catalyst compounds and use thereof | EXXONMOBIL CHEM PATENTS INC | 2012-09-12 | — | — | CN | disclosed |
| EP-2493934-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056428-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110098425-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
| US-20110098425-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098425-A1 | Catalyst Compounds and Use Thereof | ALOX12, THEM6, ALOX15 | NR1H4 2441/4885MGAM 536/4885GAA 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.