Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14741192 | 0.90 | GPR119 (0.39) | TAS1R3TAS1R1GPR119DHODH | |
| SCHEMBL14740812 | 0.88 | GPR119 (0.49) | GPR119 | |
| SCHEMBL14741143 | 0.87 | GPR119 (0.35) | GPR119DHODH | |
| SCHEMBL14757877 | 0.82 | TAS1R3 (0.36) | TAS1R3TAS1R1GAADHODHLMNA | |
| SCHEMBL16428744 | 0.79 | MAPT (0.41) | TAS1R3TAS1R1GAAGPR119LMNA | |
| SCHEMBL16428826 | 0.79 | GPR119 (0.46) | GPR119 | |
| SCHEMBL14740882 | 0.78 | ALDH1A1 (0.42) | LMNA | |
| SCHEMBL14740886 | 0.78 | MCL1 (0.47) | DHODHLMNA | |
| SCHEMBL14741032 | 0.78 | DHODH (0.36) | DHODH | |
| SCHEMBL14741298 | 0.78 | KMO (0.40) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409905-B2 | Antibacterial compounds and methods for use | PTC THERAPEUTICS, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038437-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | MRPL21, SLC11A2, CLPP | TAS1R3 3919/4885TAS1R1 3927/4885GAA 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.