Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.48 |
| ▸ | GABRP | O00591 | 6/20 | 0.48 |
| ▸ | GABRD | O14764 | 6/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.48 |
| ▸ | GABRE | P78334 | 6/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019601 | 0.92 | CYP1A2 (0.59) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL1644521 | 0.85 | POLB (0.70) | CYP1A2POLBCYP2C19ALDH1A1LMNA | |
| SCHEMBL197360 | 0.83 | CYP1A2 (0.50) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL31285451 | 0.81 | GABRA1 (0.49) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL7999648 | 0.81 | SIRT6 (0.52) | CYP1A2POLBCYP2C19GABRA1GABRG2 | |
| SCHEMBL600789 | 0.81 | GABRA1 (0.49) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL30986210 | 0.81 | SIRT6 (0.52) | CYP1A2POLBCYP2C19GABRA1GABRG2 | |
| SCHEMBL8883054 | 0.81 | POLB (0.49) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL991765 | 0.81 | POLB (0.49) | CYP1A2POLBGABRA1GABRG2GABRB3 | |
| SCHEMBL9318633 | 0.81 | KDM4E (0.49) | CYP1A2CYP2C9CYP2C19GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314240-B2 | Sulfonamide compounds or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2305641-A1 | SULFONAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-04-06 | — | — | EP | disclosed |
| EP-1105775-B1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INC (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1105775-A4 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INC (US) | 2005-04-13 | — | — | EP | disclosed |
| US-6517746-B1 | Polarizing material is a complex of (a) elemental iodine; (b) a hydrohalide acid or an ammonium, alkali metal or alkaline earth halide; (c) a pyrazine-2,5-dicarboxylic acid; and (d) a monoamide or monoester of a pyrazine-2,5-dicarboxylic acid | RESEARCH FRONTIERS INCORPORATED | 2003-02-11 | — | — | US | disclosed |
| EP-1105775-A1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INCORPORATED (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000003178-A1 | POLYHALIDE PARTICLES AND LIGHT VALVES COMPRISING SAME | RESEARCH FRONTIERS INCORPORATED (US) | 2000-01-20 | — | — | WO | disclosed |
| US-4120762-A | POROUS SUPPORT IMPREGNATED WITH AN ELECTROLYTE, A MARKING COMPOUND AND A NITROGEN-CONTAINING SIX-MEMBERED HETEROCYCLIC AROMATIC CARBOXY ACID | ALDEN RESEARCH FOUNDATION (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201616-A1 | SULFONAMIDE COMPOUNDS OR SALTS THEREOF | PTGER1, PTGER2, GPER1 | CYP1A2 1777/4885POLB 4796/4885CYP2C9 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.