Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439402 | 0.89 | MAPT (0.42) | ALDH1A1KDM4EMAPTMAPK8MEN1 | |
| SCHEMBL165699 | 0.87 | GRM4 (0.38) | GRM4TDP1PKML3MBTL1 | |
| SCHEMBL271720 | 0.80 | SCD (0.35) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL270669 | 0.76 | TSHR (0.32) | ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL271937 | 0.76 | POLB (0.37) | ALDH1A1MAPTSMN1; SMN2KMT2AGRM4 | |
| SCHEMBL272118 | 0.75 | KEAP1 (0.35) | ALDH1A1KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL270665 | 0.74 | BMP1 (0.38) | ALDH1A1HTTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL167188 | 0.73 | TDP1 (0.38) | ALDH1A1SMN1; SMN2KMT2AGRM4TDP1 | |
| SCHEMBL271627 | 0.73 | MMP1 (0.39) | SMN1; SMN2TDP1 | |
| SCHEMBL271853 | 0.73 | ADAMTS4 (0.35) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611815-A1 | HERBICIDE-EFFECTIVE PYRIDYL KETOSULTAMS | Bayer Intellectual Property GmbH (DE) | 2013-07-10 | — | — | EP | disclosed |
| US-20120065065-A1 | HERBICIDALLY ACTIVE PYRIDYLKETOSULTAMS | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2012028580-A1 | HERBICIDE-EFFECTIVE PYRIDYL KETOSULTAMS | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065065-A1 | HERBICIDALLY ACTIVE PYRIDYLKETOSULTAMS | PDXK, CBR3, CBR1 | CASP3 306/4885SENP8 4824/4885SENP7 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.