Chlorpyrifos-Methyl

Chlorpyrifos-Methyl

SCHEMBL16446205

CCOP(=S)(OCC)Oc1ccc(SC)c(Cl)c1Cl.COP(=S)(OC)Oc1nc(Cl)c(Cl)cc1Cl

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 3/20 0.62
MAPT P10636 2/20 0.62
TSHR P16473 2/20 0.62
HSD17B10 Q99714 2/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
MAPK1 P28482 1/20 0.62
ATM Q13315 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 2/20 0.37
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA3 P07451 1/20 0.33
HPGD P15428 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorpyrifos SCHEMBL1069405 0.84 ALDH1A1 (0.89) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL9300722 0.83 ALDH1A1 (0.61) TDP1ALDH1A1CYP3A4MAPTTSHR
SCHEMBL118866 0.81 TDP1 (0.54) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL21680 0.79 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL7908295 0.79 ALDH1A1 (1.00) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL29011072 0.78 ALDH1A1 (0.97) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL28566223 0.78 ALDH1A1 (0.97) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL28945660 0.78 ALDH1A1 (0.97) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL18228939 0.78 ALDH1A1 (0.97) TDP1ALDH1A1CYP3A4MAPTTSHR
Chlorpyrifos SCHEMBL28343022 0.78 ALDH1A1 (0.97) TDP1ALDH1A1CYP3A4MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015018870-A1 AGROCHEMICAL FORMULATIONS WITH IMPROVED DRIFT CONTROL LAMBERTI SPA (IT) 2015-02-12 WO disclosed