SCHEMBL16446616

SCHEMBL16446616

Cc1ccc(C)n1-c1cc(I)n(C)n1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6125259 0.81 BAZ2B (0.37) KDM4EALDH1A1L3MBTL1
SCHEMBL1064764 0.76 KDM4E (0.33) KDM4EALDH1A1L3MBTL1
SCHEMBL10537 0.76 KDM4E (0.38) KDM4EALDH1A1L3MBTL1
SCHEMBL24008182 0.73 KDM4E (0.32) KDM4EALDH1A1L3MBTL1
SCHEMBL17796670 0.72 ALDH1A1 (0.33) KDM4EALDH1A1L3MBTL1
SCHEMBL17796551 0.72 KDM4E (0.31) KDM4EALDH1A1L3MBTL1
SCHEMBL17796453 0.72 KDM4E (0.34) KDM4EALDH1A1L3MBTL1
SCHEMBL14814435 0.71 POLB (0.42) KDM4EALDH1A1
SCHEMBL14814216 0.71 MAPK1 (0.39) ALDH1A1L3MBTL1
SCHEMBL17687609 0.71 KDM4E (0.30) KDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2024-12-05 — — US disclosed
CN-113582889-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2024-09-20 — — CN disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2022-04-14 — — US disclosed
CN-113582889-A Sulfonylureas and related compounds and uses thereof 昆士兰大学 2021-11-02 — — CN disclosed
CN-113563264-A Sulfonylureas and related compounds and uses thereof 昆士兰大学 2021-10-29 — — CN disclosed
EP-3888749-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2021-10-06 — — EP disclosed
EP-3888749-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2021-10-06 — — EP disclosed
EP-3030082-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES Syngenta Participations AG (CH) 2016-06-15 — — EP disclosed
EP-3030080-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES Syngenta Participations AG (CH) 2016-06-15 — — EP disclosed
US-20160159819-A1 CHEMICAL COMPOUNDS SYNGENTA LIMITED (GB) 2016-06-09 — — US disclosed
US-20160159819-A1 CHEMICAL COMPOUNDS SYNGENTA LIMITED (GB) 2016-06-09 — — US disclosed
US-20160159819-A1 CHEMICAL COMPOUNDS SYNGENTA LIMITED (GB) 2016-06-09 — — US disclosed
WO-2015097043-A1 DIHYDRO-HYDANTOIN DERIVATIVES WITH HERBICIDAL ACTIVITY SYNGENTA PARTICIPATIONS AG (CH) 2015-07-02 — — WO disclosed
WO-2015018434-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-02-12 — — WO disclosed
WO-2015018433-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-02-12 — — WO disclosed
WO-2015018434-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-02-12 — — WO disclosed
WO-2015018433-A1 PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-02-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP KDM4E 3179/4885ALDH1A1 3558/4885L3MBTL1 4128/4885
US-11845715-B2 — NLRP3, PYCARD, NOD1 KDM4E 3154/4885ALDH1A1 3407/4885L3MBTL1 2907/4885
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP KDM4E 3179/4885ALDH1A1 3558/4885L3MBTL1 4128/4885
US-20160159819-A1 CHEMICAL COMPOUNDS RDX, CBR3, RRS1 KDM4E 891/4885ALDH1A1 237/4885L3MBTL1 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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