Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224765 | 0.88 | POLB (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL12516600 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL2221372 | 0.84 | LMNA (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL3436573 | 0.82 | MEN1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3436336 | 0.82 | ALDH1A1 (0.48) | AKR1C3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12516601 | 0.79 | CXCR3 (0.53) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| SCHEMBL3436767 | 0.79 | AKR1C3 (0.48) | AKR1C3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10148332 | 0.78 | L3MBTL1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL25216959 | 0.77 | MAPT (0.63) | ALDH1A1SMN1; SMN2GAAKDM4ETP53 | |
| SCHEMBL25274982 | 0.76 | LGMN (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952004-B2 | CXCR3 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-10 | — | — | US | disclosed |