Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14344232 | 0.77 | MAPT (0.69) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL1104364 | 0.76 | ALDH1A1 (0.55) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL5456024 | 0.76 | ALDH1A1 (0.57) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL25443596 | 0.76 | ALDH1A1 (0.55) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL3965377 | 0.76 | ALDH1A1 (0.55) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL22230672 | 0.75 | ALDH1A1 (0.62) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL10220402 | 0.73 | ACSS2 (0.64) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL12963860 | 0.73 | ALDH1A1 (0.56) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL12376560 | 0.73 | PIK3CD (0.53) | ACSS2ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL29957076 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2TDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150045551-A1 | FUSED AZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045551-A1 | FUSED AZOLE DERIVATIVE | AVPR1B, AVPR1A, GRIN2B | ACSS2 2125/4885ALDH1A1 1108/4885SMN1; SMN2 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.